The Placebo Effect - An Overview

‘I will follow that system of regimen which, according to my ability and judgment, I consider for the benefit of my patients, and abstain from whatever is deleterious and mischievous.’ Hippocratic Oath (1)

There is a large and burgeoning literature on the phenomenon of the ‘placebo effect’, that is, the tendency of people experiencing illness to improve through an engagement with a medically inactive remedy, ranging from sham surgery to administration of an inert injection or oral medication.
Most recently this literature is inspired by the increasing use of antidepressant medications in the treatment of major depressive disorders (MDD’s), where ‘fewer than half of the depressed patients who receive active medications in psychiatric trials show clinically significant improvement’ and where placebo medication has been shown to be effective in up to 70% of cases. (2)

Apart from MDD’s, people taking placebos often report reduction in pain, healed ulcers, eased nausea and even disappearing warts. The literature rarely denounces the existence of a placebo effect; disagreement and controversy arises most often in understanding how it comes about, and more importantly, how it might be used.

It can be argued that the foundation of modern western medicine resides in the distinction between ‘mind’ and ‘body’, the former understood as a philosophical construction which places it outside the realm of medical practice (unless seen, in the psychiatric model, as a function of the brain and nervous system), the latter as a kind of sophisticated machine. This machine can ultimately be understood analytically, through an understanding of its functional components and their complex interactions.

The placebo effect disrupts this assumption of a mind-body boundary, especially where conventional medicine relates it dismissively to complementary and alternative medicines (CAM’s): ‘You may think that such-and-such was effective, but it was only a placebo effect.’ This misses the point. To dismiss, say, homeopathy as ‘merely a placebo’ is not to dismiss it at all, since there is a tacit recognition that there is in fact a placebo effect, that in a greater or lesser degree, the thing actually works.

The fact that it works outside the reductionist and analytical paradigm is the real issue. Put this way, it is not an argument about therapies, but an argument about prestige and power, played out socially, culturally, politically and economically.

Refs:
(1) Hippocratic Oath
(2) Richard Entsuah, Phil Vinall, Potential Predictors of Placebo Response: Lessons From a Large Database. Drug Information Journal. Ambler: 2007. Vol. 41, Iss. 3; pg. 315, 16 pgs

Homeopaths have actually

Homeopaths have actually used placebo as healing tools throughout the history of homeopathy--and this is well documented in case notes, writings, and clinical data compiled by homeopathic doctors over the last two and a half centuries.

I used to think using them was unethical, and sneaky--but I know that they can be used effectively to help patients feel like they've got more control over the process of restoring their health (many patients have a hard time adapting to the reality of "less is more" in homeopathy, the idea that you don't have to take medicine every day, forever, like you do in the conventional medical treatment methods).

I have to say, as well, that placebo tend to have an effect that is very different from the effects of actual homeopathic medicines. Yes, a patient can heal from the use of placebo, but in my experience, they can also aggravate with the use of placebo! So there's quite a lot to be said for the power of suggestion in the context of treatment, especially in patients who are susceptible to suggestion to begin with. In any case, it certainly helps as a practitioner to have this insight into your patient, even if the placebo's effects are limited to demonstrating that truth.

Readers may be interested in

Readers may be interested in my blog article on how to use the placebo effect to improve outcomes. <a href="http://powerstates.com/?p=169">http://powerstates.com/?p=169</a>.
Thanks for a great resource!

I myself, have been

I myself, have been diagnosed with ulcerative colitis to which I have taken mainstream pharmaceuticals to which I had side effects. I started on my journey of natural medicine and found the placebo as it is called effect I can now eat as I like and lead a virtual colitis free life it has helped myself and my daughter through health and life situations to this I am ever grateful. My wish is that people would stand and take notice

See also the spoof 'Sugapil'

See also the spoof 'Sugapil' site

http://www.sugapil.com

I think a big enemy of the

I think a big enemy of the placebo effect, and one which enhances the power of the pharmaceutical companies, is the push to regard everyone as a "client", or worse still, a "consumer"

In my exprience, a patient comes and says "help me heal"; a "consumer" says "cure me" (often with an implied 'or else')

It takes a very special set of skills, and time, and good humour, to get the "consumers" to a stage where they can activate their placebo capacity.

Camilla, GP, Brisbane